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DepMap 24Q2 Public

Dos Reis et al., 2024)

After briefly summarizing how ROS trigger a DNA damage response, we concentrate on recent studies implicating a role for mitochondrial DNA (mtDNA) damage and repair mechanisms focusing on 8-oxoguanine DNA glycosylase (Ogg1) as well as crosstalk between ROS production, mtDNA damage, p53, Ogg1, and mitochondrial aconitase (ACO2)

Curr Opin Clin Nutr Metab

Desai S, Chan L, Handog E, Djojoseputro L, Lim J, Ling R, Nguyen H, Tam E, Tang J, Thng S, Tran H
