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it inhibits microglial activation and has been shown to reduce serum levels of inflammatory cytokines in toxininduced parkinsonian rats [43, 44]

This includes the use of advanced analytical techniques (e.g., liquid chromatography-mass spectrometry) to quantify TCM components and their metabolites in plasma, gut, and liver tissues, as well as the integration of pharmacokinetic and pharmacodynamic data to establish doseresponse relationships

doi: 10.7150/thno.68972 123 DenkertCLiedtkeCTuttAvon MinckwitzG

Reducing the dose of cisplatin, or replacing it with another chemotherapeutic agent, requires randomized clinical trials to prove equal efficacy, otherwise this could negatively affect survival

N-methylated glutathione analogues demonstrate a 16.1-fold increase in oral bioavailability compared to native GSH