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However, it may have little effect once the damage becomes too advanced

Nuclear IGF-IR can not only bind to IGF-IR promoter DNA and promotes the transcription of itself [85], but also directly binds DNA and recruit RNA polymerase II to upregulate JUN and FAM21 expression in cancer cells [86]

14JJ7044), the Project Foundation of Health Department of Hunan Province (grant no

doi: 10.1016/0278-5846(86)90023-0 265 PakravanD.OrlandoG.BercierV.Van Den BoschL

References 1 AhmadA
