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When the patient recalls a specific injury that led to the pain and swelling, the swelling often does not occur until the day after the injury

Therapeutic strategies aimed at targeting pathogenic antibody responses, such as intravenous immunoglobulin treatment, which is widely recognized for its anti-inflammatory and immunomodulatory effects, show promise in alleviating symptoms and enhancing patient outcomes [29,92,93,94,95,96,97]

MCAS, liver function, and a few other possibilities deserve a workup

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