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Conflict of interest LB is employed by company Pregmama, LLC, Gaithersburg, MD, United States

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How should healthcare providers approach the risk-benefit analysis for these treatments

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Phase 3 CagriSema (Garvey et al., NEJM 2025

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Once activated, caspase-3 initiates the cleavage of a downstream substrate, such as nuclear poly (ADP-ribose) polymerase (PARP), which facilitates cellular disassembly and serves as a biomarker of cell apoptosis

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It can also be effectively used for PCOS treatment, as well as other female dysfunctions

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