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Introduction Reactive oxygen species (ROS) are physiologically produced by aerobic cells [1] and their production increases under conditions of cell injury [2]

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For instance, selenoproteins S (SELENOS), N (SELENON), M (SELENOM), T (SELENOT), and F (SELENOF, previously known as 15 kDa selenoprotein (Gladyshev et al., 2016) are endoplasmic reticulum-associated proteins, involved in the unfolded protein response (Ye et al., 2005) and, potentially, other less explored functions