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Avoid use with direct acids, retinoids, and strong antioxidants
Endocr Rev 30(4):376408
The double-blind placebo control in this study eliminates this as an explanation for the results
J.DemarM.VingronM.et al
ERT is also potentially limited by reaccumulation of Gb3 in podocytes after dose adjustment during the follow-up period and formation of neutralizing antidrug antibodies after infusion, which reduce the efficacy of ERT by increasing cellular Gb3 deposition and results in harmful clinical outcomes that include progressive loss of renal function 13,14
