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If your diet will not allow such food groups, ie Vegans and Vegetarians or you have a medical condition that dictates an intolerance to these specific food groups, it can cause a Vitamin B12 deficiency therefore B12 injections can be very beneficial

Haematological effects of oral cobalamin preparations on patients with megaloblastic anaemia

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As a result, some patients experience worsening symptoms after switching from PN to PLP [35]