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Proteomics 14: 829838 Sullivan CR, Koene RH, Hasselfeld K, O'Donovan SM, Ramsey A, McCullumsmith RE (2019) Neuronspecific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia

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6.1.3 Impaired quality control Persistent LPOinduced damage ultimately impairs mitochondrial quality control mechanisms

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Nevertheless, our findings in erythrocytes and previously published in SCD cardiac tissues 46 support that, in addition to inflammation suppression 23 and fetal globin induction 31,63,64 , DMF displays anti-oxidative and ferroptosis stress effects to alleviate SCD clinical severity, and therefore, might be pursued as a new treatment option