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144 These inhibitors hold promise for slowing disease progression and preserving cognitive function in affected individuals

10.1080/10826068.2020.1734942 [DOI] [PubMed] [Google Scholar] Wang, Y

In BV2 microglia, ATP/P2X7-dependent Ca 2+ influx gates the SUR1TRPM4 channel, promoting Na + entry, membrane depolarization, and secondary K + effluxa canonical trigger for NLRP3 inflammasome assembly [99]

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To further investigate whether LC3B is expressed in RGCs, we performed co-localization studies using antibodies against LC3B and RBPMS, in EAAC1 KO mice