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This study was approved by the Ethic Committee of School of Medicine, University of Zagreb (Project code: 380-59-10106-17-1001290

In patients receiving the methylcobalamin alone, pain scores had decreased significantly by 23% at the end of treatment (39)

The year 2024 can only be assessed after completion

When M2 macrophages were transfected with the IVT mRNA-loaded nanoparticles, gene expression profiles revealed a shift from M2 to a phenotype that more closely resembled the phenotype of inflammatory macrophages (generated separately by culturing BMDMs with TLR4)