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Ibrahim et al., 2020

doi: 10.1159/000212963

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By upregulating LHCGR mRNA and downregulating FSHR and CYP11A1 mRNA, it affects steroidogenesis [133]

Histamine H Receptor Antagonist (H 2 RA)/Proton Pump Inhibitor (PPI) Induced Vitamin B 12 Depletion Literature suggests that drugs which suppress stomach acid production such as PPIs 159163 and HRAs 164167 interfere with vitamin B 12 absorption, by reducing dietary B12 release from food proteins