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However, if split dosing improves your adherence and reduces side effects, the practical benefit may outweigh theoretical pharmacokinetic concerns

Deficiency symptoms include anaemia, fatigue, neurological manifestations such as paraesthesia and balance problems, and glossitis, with neurological damage potentially irreversible if untreated

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The reasoning is that oral bioavailability is ~4050%, and animal study HED conversions suggest higher doses may be needed for the full effect
