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External and iatrogenic causes: Excessive supplementation: High-dose oral supplements or frequent intramuscular injections (hydroxocobalamin or cyanocobalamin) can elevate serum levels, though this rarely causes problems

In animal studies, MOTS-c has demonstrated near-miraculous effects on metabolic health

Older Adults and Vitamin B12 Older adults are at a higher risk of vitamin B12 deficiency due to poor absorption, gastrointestinal disorders, and decreased dietary intake