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However, the exact intracellular mechanism that contributes to inducing this oxidative stress is not completely understood ( Iron has been discovered to play a part in APAP-caused hepatotoxicity
As such, microglia serve a key role in neurological disorder
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Systemic drugs Sorafenib, the first tyrosine kinase inhibitor authorized for the treatment of patients with unresectable HCC, advanced renal cell carcinoma, and differentiated thyroid cancer, 210 has been shown to trigger ferroptosis by inhibiting system xc- and increasing intracellular iron levels
