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Natural history Several series of patients with prolactin-secreting microadenomas observed for long periods without treatment have shown that the risk of progression to macroadenoma over 10 years is small (about 7%).8 In some cases, prolactin levels returned to normal in patients who did not receive treatment or who received treatment intermittently with dopamine agonists

Rat CTR1 (rCTR1) can transport copper and platinum drugs, and makes cells susceptible to their cytotoxicity (Liu et al., 2009

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doi: 10.1056/NEJMra1600266

For instance, PS-NPs, with sizes comparable to cell membrane pore diameters (approximately 100 nm), can penetrate the BBB directly, invade the central nervous system, and interfere with neuronal function, making them a major focus of current research 11