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The ferroptosis inducer erastin irreversibly inhibits system xc- and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells
The ACSL4 inhibitor rosiglitazone (Rosi) can also alleviate diabetic kidney damage by inhibiting ferroptosis (135)
[DOI] [PubMed] [Google Scholar] 14.Adhikari A., Mondal S., Darbar S., Pal S.K
10.1021/acs.orglett.7b01534
It is predicted that by 2045, the total number of individuals with diabetes will be 783 million, representing a prevalence rate of 12.2%
