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Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal, further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly (for parenteral supplementation) or daily (for oral supplementation)

This study was supported by the Romanian Executive Agency for Higher Education, Research, Development, and Innovation ( accessed on April 20, 2023) research project FDI 0690/2023, the Analysis of the potential for sustainable use of vegetation specific to the Danube-Danube Delta-Black Sea System project, awarded by the European Regional Development Fund through the Competitiveness Operational Program 20142020, contract no

Key numbers Oxidative only: G6P Ru5P + 2 NADPH + CO Full cycle (6 G6P in): 6 G6P + 12 NADP 5 G6P + 6 CO + 12 NADPH (net 1 G6P oxidized, 12 NADPH made) Thus PPP is the cells flexible supplier of reducing power and ribose, letting any tissue match antioxidant and biosynthetic needs without leaving central carbon metabolism