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Aceclofenac is commonly prescribed for: Osteoarthritis Rheumatoid arthritis Ankylosing spondylitis Post-surgical inflammation Musculoskeletal pain and lower back pain Because of its longer half-life, it provides sustained relief with twice-daily dosing

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Patients are typically pre-medicated with folic acid, vitamin B12, and a corticosteroid (like dexamethasone) to help reduce the incidence and severity of some of these side effects, particularly skin reactions and bone marrow suppression