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If you are treating your underactive thyroid but still feel "run down" or are experiencing neurological symptoms like tingling in your fingers, it is a strong signal that you should investigate your B12 levels
In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose

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Regulatory status varies by country and by specific peptide