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A 2018 study in the journal Nutrients found that L-glutamine supplementation enhanced the function of various immune cells, particularly in times of stress or illness (Cruzat et al., 2018)

For instance, vitamin D deficiency enhances oxidative stress and impairs mitochondrial dynamics, both implicated in PD pathology [155]

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Another major role of glutamine metabolism is the provision of oxaloacetate (OAA) in order to sustain the TCA cycle, a process called anaplerosis

Willems L, Jacque N, Jacquel A, Neveux N, Maciel TT, Lambert M, Schmitt A, Poulain L, Green AS, Uzunov M, Kosmider O, Radford-Weiss I, Moura IC, Auberger P, Ifrah N, Bardet V, Chapuis N, Lacombe C, Mayeux P, Tamburini J, Bouscary D