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Biochemical Structure and Copper-Binding Mechanisms Molecular Architecture of the GHK-Cu Complex The GHK-Cu peptide complex exhibits a specific molecular weight of 340 Da, comprising the tripeptide backbone (Gly-His-Lys) coordinated with a single copper(II) ion

Taken together, these findings suggest that other system enzymes, in addition to MDHAR, may not be a rate-limiting step in ascorbate recycling

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doi: 10.1016/j.colsurfb.2019.110465

HBP overactivation also leads to endothelial dysfunction, endoplasmic reticulum stress, and accelerates atherosclerosis, contributing to cardiovascular damage [97]