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Based on the time lapse from onset to diagnosis, it was considered highly likely that the tumor originated in the extracranial subcutaneous region and invaded intracranially with skull destruction

Therefore, although the genetic role in PD has not been studied intensively, current data may suggest that various unknown genetic changes contribute to the pathogenesis of PD, providing potential targets for genetic therapy

For instance, neonatal mice inoculated with vaginal microbiota from women dominated by Lactobacillus crispatus versus those with Gardnerella vaginalis and Atopobium vaginae show differential outcomes in metabolism, immune function, and neurodevelopment (Jaarevi et al., 2021