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Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges

Bertelli A, Giovannini L, Palla R, Migliori M, Panichi V, Andreini B: Protective effect of L-propionylcarnitine on cyclosporine-induced nephrotoxicity

This review summarizes the currently known drugs, natural compounds, probiotics, and prebiotics that can reduce the level of TMA and TMAO

Some articles not indexed on PubMed were identified and included if they were from a peer-reviewed journal

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