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Approaches with both preclinical and clinical evidence L-arginine supplementation Rationale L-arginine supplementation to promote NO production is based on the premise that in conditions of endothelial dysfunction, intracellular L-arginine levels may become suboptimal

-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1

10.3389/fphys.2021.669356 [DOI] [PMC free article] [PubMed] [Google Scholar] 143.Sandri M, Robbins J

The alkoxyl and hydroxyl free radicals are reactive and rapidly target the major macromolecules in cells (Strzelak et al., 2018)

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