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Description
Unlike earlier compounds that affected multiple methyltransferases, 5-amino-1MQ demonstrates remarkable specificity for NNMT without inhibiting related SAM-dependent enzymes or components of the NAD+ salvage pathway
Scientific Reports 8:3660
n = 8), while a second group received 5A-1MQ treatment at 32 mg/kg of active pharmaceutical ingredient (injections of 4 mg 5A-1MQ monochloride salt/mL sterile saline dosed at 10 mL/kg body weight) after being switched from WD to LD (termed the WD/LD-T group
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