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Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial

Vitamin B12 supplementation can be an important part of treatment for dogs with any of these conditions: Small intestinal bacterial overgrowth (SIBO) Surgeries that shorten bowel length Cancer of the intestinal tract Familial cobalamin deficiency (a genetic condition) Eating a vegan diet that isnt designed by a veterinary nutritionist Veterinarians will routinely run blood tests to check a dogs vitamin B12 levels after they have diagnosed any of these health problems or if the dog has symptoms that fit with a vitamin B12 deficiency

There's a real grain of truth here

Deficiency of vitamin B12 vitamin may cause damage to blood vessels due to increase in the levels of homocysteine in the body

And quite often, it points to the same thing: low vitamin B12