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Among these four isoforms, AK1C2 and AK1C3 share 87.9% amino acid sequence identity and both enzymes possess 3-hydroxysteroid dehydrogenase (3-HSD) activity and catalyze 5-dihydrotesterone reduction to produce 5-androstane-3,17-diol (3-diol) 30
Histamine H3 Receptors Inhibit Serotonin Release in Substantia Nigra Pars Reticulata. The Journal of Neuroscience, vol
Srednicka et al., 2021)
& Sohal, J
