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(More information) The use of cholesterol-lowering medications called statins can decrease circulating coenzyme Q 10 concentrations

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After 50 days of continuous administration followed by 14 days of drug withdrawal, the total sperm motility of mice was almost 0, and a large number of abnormal eosinophilic spermatogenic cells appeared in the testis

At day 32, pathological motor and sensorimotor behaviors were evaluated by rotarod, grip strength, cylinder and pole test as these motor tests have been validated in the chronic rotenone mouse model and are surrogate markers for some of the motor abnormalities seen in PD patients 1,31,33,34