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Bhagirath AY, Li Y, Somayajula D et al (2016) Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

76 The demonstration of cellular NODE catabolism, with prostaglandin reductase-1 identified as a functional nitroalkene reductase, has also provided a satisfying endogenous mechanism to halt such nitro fatty acid-dependent signaling cascades

One solution may be targeting the last molecule within the signaling pathway

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