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Cureus / PMC (2024) 9
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These two results were significantly correlated, and the authors concluded that oxidative stress is an early event in the progression of kidney disease (Gazdkov 2001)
Although some patients develop a mild rash to allopurinol that remains mild over time, or respond to antihistamines, continuing the allopurinol despite a rash is not advised, since the rash can worsen unpredictably
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