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The treatment was too weak, wore off in 6 weeks instead of 3 to 4 months, or never worked at all
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Multiple paxillin binding sites regulate FAK function
Regulatory agencies apply stricter benefit-risk thresholds for obesity treatments than for life-threatening conditions, and tesofensines stimulant-like cardiovascular effects did not meet that threshold despite producing 10% mean weight loss
These models help scientists investigate how peptide-based signals influence different biological pathways in controlled experimental conditions
