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Homocysteine is cytotoxic to the cells and needs either to be remethylated via methionine synthase requiring folate as the methyl donor or betaine homocysteine methyltransferase using betaine (also known as trimethylglycine) as the methyl donor or eliminated via the transsulfuration pathway (Figure 1(a)

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In this regard, alternatives are required

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Melanin is the pigment responsible for skin colour and excess melanin often leads to dark spots, uneven tone and dullness

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