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GLP-1 receptor agonists are modified versions of this peptide, engineered to resist the rapid degradation that limits the natural hormone's half-life to just a few minutes

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Enolase also catalyzes the reverse reaction during gluconeogenesis converting PEP to 2-PG

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Benton CB, Takahashi K, Bose P, Wang F, H-C C, Zheng X, Zhang J, Wang X, Su X, Montalban-Bravo G, Issa GC, Daver N, Jabbour EJ, DiNardo CD, Bueso-Ramos CE, Patel K, Kornblau SM, Konopleva M, Borthakur G, Kadia TM, Cortes JE, Ravandi F, Andreeff M , Garcia-Manero G, Futreal A, Kantarjian H