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The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: the role of the endothelial network

24 Compared with solvent treatment, populations of control (EV) RNAi animals treated with metabolite have significantly greater fragmentation characterized by circularly shaped mitochondria, which is potentially indicative of increased mitophagic activity due to decreased mitochondrial fission and more rapid turnover of mitochondria (Figures 5a and b)

such rapid effects in human striatum may indirectly affect prefrontal glutamate levels, given the relationship between striatal dopamine and prefrontal glutamate [10]

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The danger with CKD is the feedback loop