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Interestingly, recent research has shown that the immunoregulatory induction of maternal Treg cells can prevent autism-like behaviors in adult progenies [24], raising the need for bile salt metabolic regulation in mothers to be explored more to reduce ASD risk in offspring

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Recently, additional evidence of the link between GPX4 mutations and SSMD was presented by Fedida, who performed WES on dry blood spot samples of two affected siblings [14]