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Enhancing GSH, mainly through NAC, GSH precursors rich in cysteine (whey protein, whey protein isolate rich in cysteine) or pro-GSH compound administration, becomes a potential treatment option for inflammatory diseases by reducing oxidative stress and cytokine expression especially in diabetic patients that also are at risk of more severe COVID-19 disease (299)

Neurotherapeutics 5:421432 Wang W, Ballatori N (1998) Endogenous glutathione conjugates: occurrence and biological functions

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doi: 10.1007/s00125-010-1764-2 93 MikkelsenKHKnopFKFrostMHallasJPottegrdA

It is increasingly recognized that these glycosides are generally believed to require hydrolysis in the intestinal lumen by host enzymes or gut microbiota into more membrane-permeable aglycones for efficient absorption (Nakamura et al., 2020)