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Description

GB, also called as original betaine (N,N,N-trimethylglycine) was first discovered from Beta vulgaris which is later found to be distributed in microorganisms, plants and animals

Introduction Melatonin ( N -acetyl-5-methoxytryptamine) (MEL) is synthesized from tryptophan and exhibits various biological activities in humans

Various standardized scales, such as the Numerical Rating Scale, Dermatology Life Quality Index, and 5D Itch Scale, serve as objective metrics in clinical settings, evaluating diverse facets of itching encompassing its intensity, distribution, and associated conditions like anxiety, depression, and insomnia, along with overall quality of life (22)

Int J Pept Res Ther 28:87 Veldhuizen EJ, Schneider VA, Agustiandari H, van Dijk A, Tjeerdsma-van Bokhoven JL, Bikker FJ, Haagsman HP (2014) Antimicrobial and immunomodulatory activities of PR-39 derived peptides