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Oral forms can degrade in the digestive system, limiting their impact

Previous studies have suggested that the possible synthesis sites of estradiol in crustaceans are the ovary and the hepatopancreas, and its synthesis is converted from cholesterol under the action of a series of enzymes (49), including 17-hydroxysteroid dehydrogenase ( 17 -HSDs ), aromatase, and 17-hydroxylase found in crustaceans such as Marsupenaeus japonicus (55)

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To do that it has to break down to its active form, sorbic acid
