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This is why its so important to share your full health history, including any supplements you take, with your provider

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Individuals with heart disease or unmanaged hypertension should refrain from taking PT-141, as it may elevate blood pressure

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[1] [2] As of 20242025, retatrutide remains under clinical investigation and has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom, nor by the European Medicines Agency (EMA) or the US Food and Drug Administration (FDA) for routine clinical use