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TSC-deficient cells were found to have depleted IRS-1 mRNA, an effect that is reversed by treatment with rapamycin, which inhibits unrestrained mTORC1 activation (122, 290)
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Lonstein JS, Simmons DA, Swann JM, Stern JM (1997) Forebrain expression of c-fos due to active maternal behaviour in lactating rats
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