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10.1016/j.febslet.2013.11.033 33 KoechlingU

This also results in the opening of the mPTP leading to uncontrolled ROS production and disrupted synaptic maturation causing autistic behaviors [127]

doi:10.1056/NEJM199911113412001 Bonaa KH, Njolstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K, Investigators NT (2006) Homocysteine lowering and cardiovascular events after acute myocardial infarction

This results in the upregulation of inflammatory molecules such as IL-6 and TNF-, which promote chronic inflammation and further enhance the SASP

1, GGCT2
