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Diabetes Metab 42

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Effect on the gut microbiome: Studies in mouse models show that 5-Amino-1MQ, when combined with diet, affects the gut microbiome, which may have long-term metabolic effects

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Endocrinol 14, 576590 (2018)

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It is also worth noting that sirtuin activity is coupled to the circadian clock, whereby SIRT1 and SIRT6 regulate the activity of the core clock transcription factors and downstream circadian transcriptome 8

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