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In another study, the plants leaves (2.0, 4.0 and 8.0 g/kg/day for 8 weeks) exhibited protective effects on cognitive dysfunction and hippocampal neuron apoptosis in streptozotocin-induced diabetic rats (128)

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
Examining Leaos legacy
In a controlled experiment melatonin was able to shift heart rate variability in company with the major circadian rhythms of cortisol, core body temperature and TSH (71)

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