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Description
This botanical drug exhibits anti-inflammatory, antitumor activity, and antimutagenic effects

Biochem Pharmacol 82:18071821 Singh JP, Zhang K, Wu J, Yang X (2015) O-GlcNAc signaling in cancer metabolism and epigenetics
Mol Endocrinol (2013) 27(3):52435.10.1210/me.2012-1330 266 BartkeASunLYLongoV

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Another area of increasing interest is the signaling role of astrocytic lactate beyond its role as an energy substrate: emerging evidence demonstrates that lactate induces histone lysine lactylation (e.g., H3K18la), activating transcription factors like Klf4 to regulate genes associated with synaptic plasticity (e.g., Arc, CREB), thereby contributing to epigenetic remodeling during long-term memory formationa mechanism that underscores metabolic signaling as a target for cognitive enhancement (Yao et al., 2023)
