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Role in hepatic physiology and pathology

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Henriques da Silva J, Borges VRdA, Pereira LdCB, Ferrari R, de Mattos RM, Barros EGdO, Palmero CY, Fernandes PD, de Carvalho PR, Pereira de Sousa V, Cabral LM, Nasciutti LE (2015) The oil-resin of the tropical rainforest tree Copaifera langsdorffii reduces cell viability, changes cell morphology and induces cell death in human endometriotic stromal cultures

Therefore, the robust assignment of ferroptosis should involve coupling of lipid-peroxidation readouts with rescue by lipophilic radical-trapping antioxidants or iron chelators and evidence of GPX4/system Xc contribution