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Without the reparation, the lesions in biomolecules lead to their structural damage, such as SSBs or DSBs of DNA and cross-linking of DNA to DNA, or DNA to proteins, eventually resulting in cell death

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Its only been a few weeks so, Im unsure if its made a difference in actual weight loss

The first step, catalyzed by glutamate-cysteine ligase (GCL), is rate-limiting and regulated by GSH (competitive inhibitor) and by cysteine availability ( GSH degradation is catalized by -glutamyltranspeptidase (GGT), an enzyme that catalyzes the cleavage of the peptide bond between cysteine and the -carboxyl group of glutamate, and the transfer of the -glutamyl moiety to water (hydrolysis), an amino acid, or a short peptide (transpeptidation) (Figure 1)