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Frontiers in bioscience (Landmark edition)

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Under the iron-rich, ROS-prone conditions characteristic of lesions, this perturbation engages a coordinated program of RCD across intersecting pathwaysnot only ferroptosis but also necroptotic and pyroptotic signalingwhile ferritin handling and mitophagy status further skew redox homeostasis toward irreversible injury in EESCs

Mancini MC, Morelli AP, Severino MB, Pavan IC, Zambalde P, Gis MM, et al