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A similar result was confirmed in 24 matched normal and tumor samples from the same patients (B)

Ungerstedt U

Also, NAC administration resulted in an improvement in the DPN scores and an alleviation in painful symptoms assessed by pain scores which improved by 40% together with a marked improvement in patients quality of life versus controls with improvement by 10.9% in NAC versus controls

Patients in the study were required to be between 18 and 75 years of age with histologically-confirmed Dukes' stage C colon cancer with at least one positive lymph node and to have undergone (within 8 weeks prior to randomization) complete resection of the primary tumor without macroscopic or microscopic evidence of remaining tumor

Reactive oxygen and nitrogen species (Ros/rns) scavenging assays, oxidative stress biomarkers, and chromatographic/chemometric assays