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An IV infusion takes longer because it includes hydration and supportive vitamins

10.1042/bj20100779 Biochem

Acetylated EGCG derivatives have shown improved cellular uptake and metabolic stability and are designed to release active EGCG through enzymatic or chemical hydrolysis at target sites, providing sustained therapeutic effects

However, this preservation of mitochondrial function creates a paradox: by maintaining the electron transport chain, CHAC1 inadvertently supplies the ROS that propagate iron-dependent lipid peroxidation ( via two convergent mechanisms: the direct depletion of glutathione and the indirect facilitation of mitochondrial ROS production, thereby coupling sustained metabolic activity to ferroptotic cell death under cysteine limitation

Begin with every other day (or only 2-3x per week) and work up to daily applications